There exists a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors inside the dorsal horn to minimize afferent soreness transmission and deliver analgesia. For that reason, medications like clonidine that target alpha-2 receptors can affect the transmission of soreness. : linked to, served by, https://deangblbz.blogcudinti.com/35904268/onolidine-an-overview