Abstract Background mRNA expression data from next generation sequencing platforms is obtained in the form of counts per gene or exon. Counts have classically been assumed to follow a Poisson distribution in which the variance is equal to the mean. The Negative Binomial distribution which allows for over-dispersion. i. https://www.remtavares.com/limited-find-Interstella-Sequin-Long-Sleeve-Mini-Dress-Black-huge-savings/