There exists a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors in the dorsal horn to decrease afferent soreness transmission and produce analgesia. Consequently, medications like clonidine that concentrate on alpha-two receptors can impact the transmission of suffering. Clonidine is distributed in breast milk; https://carlosa061ulu5.dailyblogzz.com/profile