Environmental or self-antigens and homotypic interactions result in BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other alerts with the microenvironment and raising the activation of anti-apoptotic and proliferation pathways. Chronic lymphocytic leukemia is often a properly-defined lymphoid neoplasm with pretty heterogeneous biological and medical https://emmav863rai1.theideasblog.com/profile